When the Egyptian God of Chaos inhabits a human body, he attempts to release Pure Evil into the world, thus beginning the final battle of Good vs. Evil. In order to stop him, the Librarians must decipher a series of clues within a science museum, including a mysterious warning spoken by exhibit mannequins that have come to life.
Flynn leads his fellow Librarians on a mission to rescue kidnapped Charlene, unwittingly ensnaring them in a subterranean trap filled with ancient Egyptian werewolves, led by nemesis Apep, who are determined to kill the Librarians once and for all.
A routine artifact retrieval is anything but when the artifact grafts itself to Cassandra. Meanwhile a blizzard forces Stone and Cassandra to take shelter at a mysterious hotel that is hosting a demon convention, who want the artifact for themselves.
After seeing a vision of her own death at the hands of a supernatural assassin, Baird tries to cheat fate and stop the deadly prophecy from coming true.
The librarians investigate a mysterious traveling carnival where they discover the sinister secret of a magician who has been corrupted by the use of real magic.
In order to stop the spread of pure evil, the team must find the Eye of Ra and unravel the mystery of the Bermuda Triangle; Flynn must pass a series of tests.
The obnoxious Cindy Kroger has suddenly become super-popular thanks to a magical love potion. The Librarians must stop her before she launches a love missile that would force the whole world to become her fan base.
A rash of people spontaneously combusting leads the Librarians to a holistic spa run by vampires, who have discovered the secret to walking in the sun.
When the Monkey King's sacred homeland of Shangri-La is taken over by a ruthless collector of magical artifacts, the balance of the Universe is put in jeopardy, forcing all the Librarians to come together to help save the imperiled land at what could be a terrible cost.
The Librarians' two-front battle comes to a head when the Library is simultaneously infiltrated by DOSA and Apep. Flynn, Baird, Stone, Cassandra, Ezekiel and Jenkins must all put aside their differences in an attempt to save the Library, the world and themselves.