Dr. Kelso's beautiful but unethical replacement, Dr. Maddox, shakes things up at Sacred Heart, while J.D. struggles to manage a new crop of incompetent interns and Carla helps Elliott put her ego in check.
J.D. and Turk make a huge sacrifice concerning a decade-long steak night tradition for a dying patient. Meanwhile, Dr. Maddox, the new Chief of Medicine, begins to show her true colors.
Featuring a special appearance from Sesame Workshop's "Muppets", J.D. learns a lesson about the gift of compassion, while Elliot gets scammed by intern Katie to secure a spot on Turk's team.
As his increasing workload from being Chief of Medicine begins to take a toll, the unimaginable happens when Dr. Cox reaches out to Dr. Kelso for friendship.
It's Ted's lucky day when he falls head over heels in love with an ukulele player, and Dr. Cox realizes he cannot handle everything that is thrown at him.
While Turk views an inspiring story on SportsCenter, he comes up with a new procedure which may help a paralyzed teen. Meanwhile, Dr. Cox and the janitor are suffering from romantic problems
J.D.'s ego becomes inflated after Dr. Cox finally gives him the recognition he's been waiting for. Elsewhere, the senior staff receives insight from the interns.
A combination of a full moon and some bad luck causes Sacred Heart's new crop of interns to receive their toughest case load yet while Elliot makes an important decision regarding her future as a doctor.
The Janitor and Lady invite the Sacred Heart staff to their fake wedding in the Bahamas hoping to score some loot but their scheme is about to backfire...
Things get weird for J.D. when he discovers the identity of Kim's new man as he plans to reach out to her in order to move closer to Sam. Meanwhile, Turk starts a campaign for a promotion.
Change doesn't come easy for the gang when J.D. considers moving closer to his son. Meanwhile, Turk gets comfortable as chief of surgery, while Ted and Gooch reach a new level in their relationship.
J.D. is planning on leaving Sacred Heart but before he goes there are a few things that he wants to do including; getting a hug from Dr. Cox, and learning the Janitor's real name. Elliot is ready for the next step in her and J.D.'s relationship and she begins moving her furniture into J.D.'s apartment.