When a massive fire breaks out in Griffith Park, Priority Homicide is on hand to help. Meanwhile, Brenda and Fritz are living in a small apartment and getting on each other's nerves.
Brenda and the team must determine if a murder was revenge or mere coincidence when a recently released murderer turns up dead, the victim of a hit-and-run. As usual, Brenda's personal life isn't much better: she must deal with a recently incapacitated Fritz.
Brenda suspects something more than suicide when a high-school girl is found hanged in her bedroom, and the investigation uncovers a ruthless sexual game being played at a private school.
A man wearing a surveillance wire is shot to death at point blank range in downtown Los Angeles, while interpersonal relationships on the squad force Brenda into a corner.
Det. Julio Sanchez' little brother Oscar is shot and killed, leaving Julio beside himself with grief and seeking his killer any way he can, which threatens the investigation.
When an FBI informant is the prime suspect in the deaths of two Tijuana police officers, Pope, Taylor and Brenda must deal with a public relations mess when a newspaper prints an unflattering story about Priority Homicide.
The body of a man who stole $3 million in diamonds is found in the trunk of a car and the condition of the body makes determining the cause of death impossible.
Fritz's sister agrees to use her psychic powers to help the Priority Homicide Division resolve one of their cases, and while her abilities appear to help her understand how Brenda works, they don't seem to stop her from offering misguided advice.
Brenda and Fritz's attention is diverted by problems on the job even though their wedding day has finally arrived, and bad blood between the members of the Priority Homicide Division threatens to cause one of the officers to leave the department.