Private detective Adrian Monk has brains, instincts, a photographic memory and more than a few obsessive-compulsive disorders. These traits, his ever-present handy wipes and his devoted assistant, Natalie Teeger, help him as he solves cases involving amnesia, betrayal, first loves, true loves and of course, murder. Along with Capt. Stottlemeyer and Lt. Disher, Monk is on the case and more germaphobic than ever.
When a parking garage attendant is killed and a financial analyst's hand is broken in a mysterious attack, Monk goes undercover in an office to solve the case.
When a detective dies at the police department Christmas party after drinking from a poisoned bottle of port intended for Captain Stottlemeyer, can Monk find the killer?