A homicide on the Brooklyn Bridge leads Mac and Jo all the way to San Francisco to find a missing teenage girl, but they are not sure if she is dead or alive.
The CSIs race to catch a shooter when Lindsay is injured during the attempted murder of a political candidate, and the events in the aftermath lead to a child's death.
The CSIs must delve into the high-pressure world of an elite prep schools when a student is murdered while studying for the SAT'S. Meanwhile, Lindsay returns home to Montana to visit her father and deal with some issues from her past.
The CSIs investigate a 1920s-inspired speakeasy when one of its owners is murdered and $10,000 goes missing. Meanwhile, Adam spends his day off in an unexpected way.
The CSIs investigate when a masked man is found at the bottom of a notorious skyscraper known for its history of mysterious deaths. Meanwhile, on her day off, Jo runs into a stranger with a surprising link to her past.