Sam Oliver has always been the slacker with no goals or purpose. However, his life takes an unprecedented new direction on his twenty-first birthday, when he discovers that his parents sold his soul to the devil and he must now become Satan's personal bounty hunter.
After Sam wakes up to find that everything he touches gives him a shock, he consults Satan, who tells him that this is related to his next target - an escaped soul from hell who sucks energy from power lines in order to loose it as lightning against his next victim. In order to capture the escapee Sam must use his new vessel, a remote control monster truck, given to him by Satan himself.
Sam, Ben, and Sock must hunt an escaped soul that uses insects to kill the people living at an apartment complex. Also, Sam is crushed when Andi meets a new guy who encourages her to go back to school full-time and quit her job.
Sam requests some time off to go to a concert with Andi, but the Devil refuses and points out that vacation periods are not part of his contract. Therefore, Sam is given a white dove as his next vessel and is sent to capture an escaped magician who kills anyone who does not appreciate his act.
Sam must deal with a toxic revenger when the escaped soul of a chemical company's CEO starts taking human lives. Meanwhile, the Devil delivers Sam's contract as promised... but it's a few hundred pages longer then Sam expected.
Sam discovers that demons don’t work on Halloween. Unfortunately, a depressed Devil decides to make Sam’s assignment even harder to cheer himself up. Sam and Sock capture one soul, Leon, an escapee who killed someone over a hundred years ago, but before Sam can return him Leon tries to convince them that he's changed. The Devil then sends Sam to recapture a second soul, a serial killer who plans on starting a new murder spree.
Sam and the crew go after a thrill-seeking pair of escaped souls that engineer car wrecks to keep their relationship fresh. Meanwhile, the Devil tries to set Sam up with a new girl.
Sam gets a reward from the Devil for a job well done... but finds that he's being set up for murder. Meanwhile, Sock becomes obsessed with Gladys the DMV demon.
Ben's mother and grandmother stop by the Work Bench for some supplies for their family reunion. However, things go sour when the grandmother accuses Sam of being evil and calls him Diablo. Meanwhile, Sam meets a lady who has been the Devil's girlfriend for over twenty years and wonders whether her daughter is the Devil's daughter or not.
Sam starts dating a woman that he suspects may be the Devil's daughter. Meanwhile, it turns out that money is the root of all evil when the the guys argue over what to do with money recovered from an escaped soul.
Sam desperately tries to stop an untalented musician when the latter tries to sell his soul to the Devil for rock star fame. Meanwhile, Sock is in for a big surprise when his mother returns from Las Vegas and announces that she is now married.
Sock and Sam move in together into a condo of their own and meet their new neighbors, Tony and Steve, a gay couple who is surprisingly friendly to the two slackers. However, Sam and Sock soon discover that there is more to the couple than meets the eye.
It's a demons world, as the gang encounters a demon support group with members who are trying to change their bad ways. However, not every demon is in for a change, as Sam and his friends must take down one who poses as a lawyer to unleash leeches on his victims.
Andi finally learns Sam's secret regarding the Devil after she is captured by a demon and the gang must rescue her. Unfortunately for Sam, the truth causes Andi to fear him and keep her distance. Meanwhile, Ben meets the woman of his dreams while chasing a demon at a hospital's maternity ward, but a major fact keeps them from being together.
When the Devil refuses to offer Sam any help on capturing the latest escaped soul, the gang turns to Gladys for help. Gladys then takes the guys to her demon friend Dennis who at first refuses to help but later on offers Sam a homemade vessel because he feels sorry that his parents sold his soul to the Devil. Meanwhile, Andi's ex-boyfriend Greg returns and Sam discovers that he has a plan to get her back.
After realizing that the latest escaped soul keeps surfacing back to Earth, the Devil informs Sam that a leak has sprung in Hell and tells his bounty hunter to find out how the souls are escaping back to Earth.