In the season premiere, McGarrett refuses to listen to Danny's pleas to take it easy while recovering from surgery after the body of a serial killer is left in the Five-0 headquarters with an ivory chess piece in his mouth.
When the bodies of two serial killers are found on Five-0 property with chess pieces in their mouths, McGarrett and the team hunt for a vigilante as fear grows that tourists aren't safe in Hawaii.
Five-0 must work with rogue MI-6 agent Harry Langford to find a terrorist planning to cause nuclear reactors across Europe to meltdown. Also, McGarrett and Danny ask retired FBI profiler Alicia Brown to help them find their serial killer vigilante.
Alicia awakens in her bed to find another body with a chess piece in his mouth beside her. The team hunts for a cartel boss whose soldiers are gunning for a member of the team. Kono reconnects with Rosie.
When a cache of guns is stolen from a gun range, Five-0 discovers the culprit is intent on making a dramatic and potentially deadly statement on gun violence. Also, Kono and Adam are finally reunited when he is released from prison,
On Halloween, Five-0 investigates the murder of a medium with a checkered past who was apparently scared to death by a poltergeist. Also, Kono and Adam are kidnapped by what appears to be a death cult.
Five-0 must free McGarrett's mother, Doris, when Catherine informs them that she was captured and is about to be executed after attempting to free Wo Fat's imprisoned father. Also, Chin loses his appeal to have Sara's adoption delayed, and she must move to Mexico.
When a conspiracy theorist with compelling evidence that JFK's cabinet ordered his assassination is murdered, Five-0 investigate's one of history's most notorious unsolved mysteries.
Five-0 investigates the 10-year-old cold case of a missing teen when a boy suffering from PTSD undergoes hypnosis and realizes he may have witnessed her murder. Also, Danny's sister, Bridget (guest star Missy Peregrym), visits Oahu for a business conference, and he suspects that she may be getting too close to a co-worker, on HAWAII FIVE-0
Five-0 must go up against an aggressive U.S. marshall, Lincoln, when a man wanted for murder escapes capture and seeks asylum in the sovereign land belonging to the Nation of Hawaii.
When working a murder case involving the illegal practice of shark finning, Five-0 uncovers the possibility that a former Nazi war criminal may be hiding out in an old leper colony in Hawaii.
While McGarrett and Danno celebrate Valentine's Day with their girlfriends, the rest of Five-0 investigates the murder of a man taking a class on how to land women.
McGarrett and Five-0 once again become entangled in the twisted mind games of serial killer Dr. Madison Gray when she stumbles into HPD covered in blood that matches Alicia Brown's, and claims amnesia.
MacGarrett and Danny finally track down the missing uranium, which has been used to build a bomb located in the middle of the jungle. Now, they must carefully extract the unstable explosive through treacherous terrain before it detonates.
McGarrett and Kono suspect that an abused young girl may be the victim of a sex trafficking ring on the Island. Also, Chin and Grover investigate a murder at a sober living facility.
Five-0 helps PI Harry Brown work the case of a kidnapped wealthy woman whose husband may have something to hide. Also, Rachel tells Danny that she is getting a divorce from Stan.
McGarrett and Five-0 are captured and face certain death after tracking a dangerous nemesis to the Island of Lanai. Also, Grover takes his son to Chicago where he testifies against a dirty cop from his past.
While working the murder case of one of the last survivors of the USS Arizona, McGarrett learns about his grandfather's important role at Pearl Harbor. Also, Adam uncovers bone fragments at his new construction job and asks Jerry to help him discreetly investigate.
When McGarrett gets a tip that someone is plotting a terrorist attack on Oahu, Five-0 searches for those behind it before it’s too late. Also, Chin and Abby have a very difficult decision to make.
McGarrett risks his life when Five-0 attempts their most dangerous rescue yet of young girls trapped in the sex trafficking ring they have been tracking this year. Also, Kono, deeply affected by the case, makes a life-changing decision.